CSIR-NET Life Science: Short Notes on Peptide Bond and Ramachandran Plot

By Neetesh Tiwari|Updated : June 27th, 2021

Hello Gradians,

We hope you all are safe and healthy!

Are you looking for some short and reliable notes during your CSIR-NET preparations? Then, you have come to a perfect place!

Candidates preparing for their CSIR NET exam might need to get some short study notes and strategies to apply while preparing for the key exam of their life. At this point, We at BYJU'S Exam Prep come up with short notes on the Peptide Bond and Ramachandran Plot, which comes under the Biochemistry section of the Life Science syllabus

Our experienced subject-matter experts have meticulously designed this set of short notes on G Protein-Coupled Receptor (GPCR) to give you the most standard set of study materials to be focused upon. In this cut-throat competitive world, students need to prepare themselves with the best study materials to help them learn and for their future. Therefore, here we are offering the best study notes that are reliable and can be used by the students during their preparations for the upcoming CSIR-NET 2021 exam.

Hello Gradians,

We hope you all are safe and healthy!

Are you looking for some short and reliable notes during your CSIR-NET preparations? Then, you have come to a perfect place!

Candidates preparing for their CSIR NET exam might need to get some short study notes and strategies to apply while preparing for the key exam of their life. At this point, We at BYJU'S Exam Prep come up with short notes on the Peptide Bond and Ramachandran Plot, which comes under the Biochemistry section of the Life Science syllabus

Our experienced subject-matter experts have meticulously designed this set of short notes on G Protein-Coupled Receptor (GPCR) to give you the most standard set of study materials to be focused upon. In this cut-throat competitive world, students need to prepare themselves with the best study materials to help them learn and for their future. Therefore, here we are offering the best study notes that are reliable and can be used by the students during their preparations for the upcoming CSIR-NET 2021 exam.

This post provides study notes on Peptide Bond and Ramachandran Plot for CSIR NET 2021. Every year 2 question comes directly from this part. Complete coverage of this section could fetch you 4 marks from this section. It is important to cover all section holistically if one aims to clear CSIR NET/NET-JRF in one go.

A peptide is a compound consisting of two or more amino acids. When two amino acid molecules are linked through a peptide bond, the product is called a dipeptide.byjusexamprep

  • Peptides and polypeptides are mostly linear and unbranched polymer composed of amino acids linked together by peptide bonds.
  • Peptide bonds are amide linkages formed between an alpha-amino group of one amino acid and the alpha carboxyl group of another. 
  • The reaction is a dehydration reaction: a water molecule is removed, and the linked amino acids are referred to as amino acid residues. 
  • The peptide C-N Bond has a partial double bond character. Due to the partial double bond character, two possible configurations, cis and trans, are observed for a peptide bond in polypeptides. byjusexamprep

 

  • The alpha carbon (Cα) in the centre of each amino acid is held in the main chain by two rotatable bonds. The dihedral (torsion) angles of these bonds are called Phi and Psi (Greek letters, φ and ψ). In fact, most Phi and Psi angle combinations are impossible because two atoms cannot occupy the same space.byjusexamprep

 

  • Most values of φ and ψ are not allowed due to steric interference between atoms in the polypeptide backbone and amino acid side chains.
  • The combination of φ and ψ values permitted in peptide backbone or that are not permitted due to steric constraints were first determined by G.N Ramachandran.
  • These permitted values can be visualized on a two-dimensional plot called a Ramachandran plot.

 byjusexamprep

  • The Ramachandran plot is a plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in a peptide.
  • By making a Ramachandran plot, protein structural scientists can determine which torsional angles are permitted and obtain insight into peptides' structure.

 

We hope you all understood the Study Notes on Peptide Bond and Ramachandran Plot.

Short Notes on Peptide Bond and Ramachandran Plot - Download PDF Now

 

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