Most Expected Questions of Life Science: Cell Cycle and Its Regulation! (Download PDF)

By Renuka Miglani|Updated : November 25th, 2021

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As we all know, the CSIR-NET exam is very near and there is no time left for revision. At this point of time, you must be seeking some ready-made authentic short revision notes or some important questions to practice just before the exam. How will you react if you get all these study materials at one place? It will be beneficial for you at this time right! We at BYJU'S Exam Prep comes up with the Most Important Questions of Cell Cycle and Its Regulation for Life Sciences to help you score good marks which have been meticulously designed by our experienced subject-matter experts.

So what are you waiting for? Scroll down the article below and start revising for the CSIR NET Exam, these questions will be fruitful during last-minute revision to fetch more marks in the exams. Students can also download it as a PDF file and save it for future purposes.

Most Important Questions of Cell Cycle and Its Regulation (Download PDF)

1. Some cells which are not able to divide further e.g., Nerve cells, in which phase of the cell cycle do they remain arrested?

  1. G0 Phase
  2. G1 Phase
  3. Prophase
  4. S Phase

2. Choose the true statement about the M-phase of Cell cycle.

  1. M -phase starts with Karyokinesis
  2. M-Phase starts with Cytokinesis
  3. No Karyokinesis occurs in M-Phase
  4. No Cytokinesis occurs in M-Phase

3. What is True about prophase in the cell cycle:

  1. Formation of nucleolus and disruption of the nuclear envelope
  2. Disruption of nucleolus and formation of the nuclear envelope
  3. Nucleolus disappearance and disruption of the nuclear envelope
  4. Nucleolus disappearance and formation of the nuclear envelope

4. In cell cycle a protein structure at the centromeric region of a chromosome which interacts with chromatin and is involved in the attachment of microtubule is:

  1. Kinetochore
  2. CNP Protein
  3. CDk protein
  4. Alpha protein 

5. In which phase of cell cycle chromatid is termed as chromosomes?

  1. Prophase
  2. Meta Phase
  3. Anaphase
  4. Telophase 

6. When in some cell karyokinesis occurs and cytokinesis does not and cell becomes multinucleate cell is known as:

  1. Septate cell
  2. Coenocytic Cell
  3. Acellular cell
  4. None 

7. Match the following and choose the option with the correct match.

I Colchicine                       A) Microtubule formation

II Cytochalasin                  B) Induce cell cycle arrest

III Taxol                           C) Inhibits Cytokinesis

IV P53                              D) Inhibits Microtubule formation


  1. I-B, II-C, III-A, IV-D
  2. I-D, II-C, III-A, IV-B
  3. I-A, II-C, III-D, IV-B
  4. I-C, II-D, III-A, IV-B

8. Match the following and choose the correct option.

I) Start of DNA Replication

II) Cell withdraw from Cycle


  1. IV) Cytokinesis
  2. A) Go phase
  3. B) S phase
  4. C) Division of cytoplasm
  5. D) Control of cell cycle


  1. I-A, II-B, III-D, IV-C
  2. I-B, II-D, III-A, IV-C
  3. I-B, II-A, III-C, IV-D
  4. I-B, II-A, III-D, IV-C 

9. Match the following

I) Cyclin -CDKs complex

II) CycilnA-CDK2 and Cyclin CyclinA-CDK1

III) Cyclin B-CDK1

IV) Cyclin E-CDK 2

A) Trigger S Phase

B) Responsible for M Phase

C) Regulation the completion of S Phase

D) Transition from G1 to S


  1. I-D, II-C, III-B, IV-A
  2. I-C, II-D, III-B, IV-A
  3. I-D, II-C, III-A, IV-B
  4. I-A, II-C, III-B, IV-D

10. In which organism during prophase of cell division, nuclear envelop remains intact?

  1. Fern
  2. Elephant
  3. Yeast
  4. E. coli 




Neurons and some skeletal muscle cells in which division does not occurs remain in G0 phase (quiescent phase), when cell enters to G1 phase it starts divide.


In cell division, the M phase or mitotic phase starts with karyokinesis (nuclear division) and form daughter nuclei and then cytokinesis occurs.

Solution - 3

The end of the prophase is marked with the disruption of nuclear envelop and nucleolus disappearance.

Solution - 4

The end of the prophase is marked with the disruption of nuclear envelop and nucleolus disappearance.

Solution - 5

In anaphase, kinetochore microtubules pulls apart two kinetochores at opposite direction, cohesion protein degrades each chromatid which then move towards pole and are called as chromosome.

Solution - 6

Coenocytic cell is formed when multiple nuclear division occurs without cytokinesis.

Solution - 7

In active form p53 induce cell cycle arrest that allows repair of cell and apoptosis for discarding the damage. Colchicine is a drug that inhibits formation of microtubule; Taxol drug allows the formation of microtubule but prevents them for shortening and Cytochalasin is a drug that inhibits the process of cytokinesis.

Solution - 8

In cell cycle S phase is known as the synthetic phase and is the stage when DNA replication takes place. When cell does not go for division, it re-enters the Go phase and withdraws from the cycle. CDK is cyclin-dependent protein kinase and undergoes synthesis and degradation in cell cycle involved in control of cell division, and cytokinesis is the process of cell division in which cytoplasm is divided.

Solution - 9

Cyclins and CDKs (Cyclin-dependent protein kinase) are regulatory components of the cell cycle, wherein Cyclin- CDK Complex trigger the transition from G1 to S phase, CycilnA-CDK2 and Cyclin CyclinA-CDK1 involves in regulation of the completion of S phase, Cyclin B-CDK1 is responsible for M-phase and Cyclin E-CDk2 is trigger for initiation of S phase.

Solution - 10

During prophase, disruption of nuclear envelope occurs but it is not a universal feature, in some lower eukaryotes like yeast and diatoms the nuclear envelop remains intact in prophase of the cell cycle.


Answer keys

1. A            

2. A            

3. C            

4. A            

5. C            

6. B

7. B            

8. D            

9. A            

10. C


Download Important Questions on Cell Cycle and Its Regulation  - Download PDF Here


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