Most Important Questions of Cell Cycle and Its Regulation (Download PDF)
1. Some cells which are not able to divide further e.g., Nerve cells, in which phase of the cell cycle do they remain arrested?
- G0 Phase
- G1 Phase
- Prophase
- S Phase
2. Choose the true statement about the M-phase of Cell cycle.
- M -phase starts with Karyokinesis
- M-Phase starts with Cytokinesis
- No Karyokinesis occurs in M-Phase
- No Cytokinesis occurs in M-Phase
3. What is True about prophase in the cell cycle:
- Formation of nucleolus and disruption of the nuclear envelope
- Disruption of nucleolus and formation of the nuclear envelope
- Nucleolus disappearance and disruption of the nuclear envelope
- Nucleolus disappearance and formation of the nuclear envelope
4. In cell cycle a protein structure at the centromeric region of a chromosome which interacts with chromatin and is involved in the attachment of microtubule is:
- Kinetochore
- CNP Protein
- CDk protein
- Alpha protein
5. In which phase of cell cycle chromatid is termed as chromosomes?
- Prophase
- Meta Phase
- Anaphase
- Telophase
6. When in some cell karyokinesis occurs and cytokinesis does not and cell becomes multinucleate cell is known as:
- Septate cell
- Coenocytic Cell
- Acellular cell
- None
7. Match the following and choose the option with the correct match.
I Colchicine A) Microtubule formation
II Cytochalasin B) Induce cell cycle arrest
III Taxol C) Inhibits Cytokinesis
IV P53 D) Inhibits Microtubule formation
Options
- I-B, II-C, III-A, IV-D
- I-D, II-C, III-A, IV-B
- I-A, II-C, III-D, IV-B
- I-C, II-D, III-A, IV-B
8. Match the following and choose the correct option.
I) Start of DNA Replication
II) Cell withdraw from Cycle
III) CDK
- IV) Cytokinesis
- A) Go phase
- B) S phase
- C) Division of cytoplasm
- D) Control of cell cycle
Option
- I-A, II-B, III-D, IV-C
- I-B, II-D, III-A, IV-C
- I-B, II-A, III-C, IV-D
- I-B, II-A, III-D, IV-C
9. Match the following
I) Cyclin -CDKs complex
II) CycilnA-CDK2 and Cyclin CyclinA-CDK1
III) Cyclin B-CDK1
IV) Cyclin E-CDK 2
A) Trigger S Phase
B) Responsible for M Phase
C) Regulation the completion of S Phase
D) Transition from G1 to S
Options
- I-D, II-C, III-B, IV-A
- I-C, II-D, III-B, IV-A
- I-D, II-C, III-A, IV-B
- I-A, II-C, III-B, IV-D
10. In which organism during prophase of cell division, nuclear envelop remains intact?
- Fern
- Elephant
- Yeast
- E. coli
Solutions
Solution-1
Neurons and some skeletal muscle cells in which division does not occurs remain in G0 phase (quiescent phase), when cell enters to G1 phase it starts divide.
Solution-2
In cell division, the M phase or mitotic phase starts with karyokinesis (nuclear division) and form daughter nuclei and then cytokinesis occurs.
Solution - 3
The end of the prophase is marked with the disruption of nuclear envelop and nucleolus disappearance.
Solution - 4
The end of the prophase is marked with the disruption of nuclear envelop and nucleolus disappearance.
Solution - 5
In anaphase, kinetochore microtubules pulls apart two kinetochores at opposite direction, cohesion protein degrades each chromatid which then move towards pole and are called as chromosome.
Solution - 6
Coenocytic cell is formed when multiple nuclear division occurs without cytokinesis.
Solution - 7
In active form p53 induce cell cycle arrest that allows repair of cell and apoptosis for discarding the damage. Colchicine is a drug that inhibits formation of microtubule; Taxol drug allows the formation of microtubule but prevents them for shortening and Cytochalasin is a drug that inhibits the process of cytokinesis.
Solution - 8
In cell cycle S phase is known as the synthetic phase and is the stage when DNA replication takes place. When cell does not go for division, it re-enters the Go phase and withdraws from the cycle. CDK is cyclin-dependent protein kinase and undergoes synthesis and degradation in cell cycle involved in control of cell division, and cytokinesis is the process of cell division in which cytoplasm is divided.
Solution - 9
Cyclins and CDKs (Cyclin-dependent protein kinase) are regulatory components of the cell cycle, wherein Cyclin- CDK Complex trigger the transition from G1 to S phase, CycilnA-CDK2 and Cyclin CyclinA-CDK1 involves in regulation of the completion of S phase, Cyclin B-CDK1 is responsible for M-phase and Cyclin E-CDk2 is trigger for initiation of S phase.
Solution - 10
During prophase, disruption of nuclear envelope occurs but it is not a universal feature, in some lower eukaryotes like yeast and diatoms the nuclear envelop remains intact in prophase of the cell cycle.
Answer keys
1. A
2. A
3. C
4. A
5. C
6. B
7. B
8. D
9. A
10. C
Download Important Questions on Cell Cycle and Its Regulation - Download PDF Here
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