CSIR NET 2024 | Life Science: Cellular Organization | 28 March

A late endosome can be differentiated from an early one by monitoring the

Major histocompatibility complex (MHC) molecules are encoded by a cluster of genes called MHC locus. There are several reasons why an MHC molecule on the surface of a cell is important. Which one of the following reasons is INCORRECT?

Given below is a list of some proteins known to be associated with apoptosis, their subcellular localization (but not in correct order) and possible role in apoptosis.

Choose the right combination which matches the proteins with their correct localization and role in apoptosis.

An integral membrane protein (P) has been identified as a cell surface protein of hepatocytes and is assigned to bind to hepatitis B virus (HBV) and promote its entry into cytosol. Upon binding to HBV particles, the C-terminal of P interacts with F-actin in the cytosol and in turn, helps in the entry of the HBV particles. P was successfully cloned and expressed in animal cells in culture wherein its N- terminal is exposed on the surface while the C-terminal resides in the cytosol. The recombinant protein P so expressed retains its complete structure and function. From the list of experiments given below, which one of the experiments will you perform to show that C- terminal of the protein P via interacting with F-actin helps in HBV entry?

The cytoskeleton is a cellular scaffolding or skeleton contained within a cell's cytoplasm. Which of the following is CORRECT?