Prosthetic Group and Co-enzyme
- Prosthetic group Enzymes are made up of polypeptide chains except for Ribozymes, RNA molecules with catalytic ability. Most enzymes need non-protein groups for a biological activity known as cofactors. The protein portion of the enzyme is known as an inactive apoenzyme. The biologically active and complete conjugated enzyme is known as the holoenzyme.
- Coenzymes are carriers of atoms or chemical groups or electrons. The substrates are transported from the point of generation to the point of utilization. For instance, coenzyme NAD which is involved in the oxidation-reduction reactions of glycolysis and citric acid cycle in respiration shuffles between two forms - NADH is the reduced form, and NAD+ is the oxidized form.
Differentiate between prosthetic group and co-enzyme.
The differences between prosthetic group and co-enzyme based on bond with enzymes, composition, main function, removal from enzyme, and examples are given in the form of a table.