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CSIR NET 2022 | Life Science: Inheritance Biology | 23 November

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Question 1

A man who is affected with a genetic disease is married to a normal woman. They have three children, two boys and a girl. The girl is affected with the disease and the boys are normal. What is the probability of a boy to be a carrier of this disease?

Question 2

Analyze the following table and find the order of the precursors in the biosynthetic pathway of X.

Question 3

Philadelphia chromosome occurs by a translocation between which of the given sets of chromosomes?

Question 4

Mild mental retardation, small gonads, short stature and obesity was noted in the offspring due to the loss of a particular segment of the long arm of chromosome 15 from the father. This is called Prader-Willi syndrome. The chromosome 15 is not a sex chromosome. Using this information, if the defective chromosome would have come from the mother it would cause?

I. Angelman syndrome


II. Mild retardation, small gonads, short stature and obesity in the offspring


III. Prader-Willi syndrome


IV. Severe mental retardation, seizure, lack of speech and inappropriate laughter


Question 5

Most cases of down syndrome are caused by presence of third copy of chromosome 21 associated with chromosome 21 pair , Trisomy is caused by
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