Crack CSIR NET 2021 | Life Science : (Cellular Organization) (13 September)

Metachromatic leukodystrophy (MLD) is caused by a deficiency of arylsulfatase A and affects the CNS. MLD is

The kinetochores:

Cells will usually divide if they receive the proper signal at a

Following are the mechanism occurring during regulation of activity of cyclin –CDK complexes.

identify the incorrect statement ?

P) Cyclin synthesis and degradation catalysed by Skp1 cullin Fbox (SCF) ubiquitin ligase and Anaphase promoting complex (APC)

Q) a highly conserved kinase called Wee1 brings about this inhibitory phosphorylation, and a highly conserved phosphatase called Cdc25 mediates dephosphorylation.

R) CDK inhibitor proteins (CKIs) binding makes cyclin-CDK complex active.

S) CDK inhibitor proteins that regulate CDKs in plants belong to CIP/KIP family and INK4 family.

Scientists subjected several drugs for screening inhibitors of cytokinesis in animals .It was found that Drug ‘X’ inhibited cytokinesis it binds the microtubule and prevent depolymerisation. Which could be X?